What are the responsibilities and job description for the Senior Scientist position at Actalent?
Description:
This position within the Immunology and Inflammation Area is for a rigorous scientist with preferred experience in autoimmunity and/or allergy, B cell biology and disease models driven by pathogenic antibodies. Candidate should be highly collaborative and team-driven, possess exceptional organizational skills and be capable of independently conducting in vitro and in vivo experiments. This individual will have the opportunity to support a broad pipeline in autoimmune and inflammatory diseases by validating targets, assessing the efficacy of therapeutic candidate molecules in disease models, and interrogating mechanisms of pathology that inform therapeutic strategies.
- Troubleshoot methodological and technical issues, interpret experimental data and literature, and communicate results to supervisor, department, or project team.
- Execute experiments based on projects/protocols provided and work towards independently developing project
- Collaborate and communicate efficiently with team members to coordinate complex in vivo experiments, and with other departments to facilitate cross-functional efforts
- Contribute to executing experiments involving proper handling and care of mice, general surgical techniques and the collection of blood and tissue samples.
- Develop and optimize relevant disease mouse models and the subsequent analysis of associated disease-related pathologies by flow cytometry, histology and ELISA
- Develop and execute cell-based assays to screen candidate antibodies for various research programs
- Perform ELISAs and/or MSDs to measure cytokine levels and determine antigen binding for various research program
Skills:
in vivo assays, elisa, flow cytometry, animal surgery, immunology
Qualifications:
Ph.D. in Biology, Immunology, or Cellular and Molecular Biology.
Skilled in the design of complex studies to interrogate the in vivo efficacy of novel therapeutics.
Experience with developing and optimizing mouse models of autoimmune and/or allergic diseases and the subsequent analysis of associated disease-related pathologies by flow cytomety, histology and ELISA.
Extensive experience with multi-parameter Flow cytometry and data analysis is required.
Experience Level:
Expert Level
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
- Hiring diverse talent
- Maintaining an inclusive environment through persistent self-reflection
- Building a culture of care, engagement, and recognition with clear outcomes
- Ensuring growth opportunities for our people
Actalent is an equal opportunity employer.
About Actalent
Actalent connects passion with purpose. We help visionary companies advance their engineering and science initiatives through access to specialized experts that drive scale, innovation, and speed to market. With a network of almost 30,000 engineering and sciences consultants and more than 4,500 clients across the U.S., Canada, Asia, and Europe, Actalent serves many of the Fortune 500. An operating company of Allegis Group, the global leader in talent solutions, Actalent launched as a new specialized engineering and sciences services and workforce solutions brand in 2021.
