Scientist

(ID: 2024-7347)

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

• 100% Medical, Dental & Vision Coverage for Employees


• Paid Time Off (Including Holidays)


• Employee Referral Bonus


• 401K Match


• Tuition reimbursement and professional development opportunities


• Flexible Spending Accounts:
  
  
  
  • Healthcare (FSA)
  
  
  • Parking Reimbursement Account (PRK)
  
  
  • Dependent Care Assistant Program (DCAP)
  
  
  • Transportation Reimbursement Account (TRN)
  
  
  
  

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Scientist to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Vaccine Production Program (VPP), Vaccine Research Center (VRC).

• Assist the Federal Task Leader (FTL) to ensure the scientific rigor for immunoassay and broader scope of analytical assays. 
• Collaborate with scientists in other departments from upstream, downstream and formulation development groups to provide assay support and optimize analytical assays. 
• Author experimental plan (EP), lead and carry out new method development and characterization plan, trouble shoot, execute, and coordinate experiments that will lead to conclusions. 
• Write technical reports and manuscripts with scientific rigor. Write one or more per year reporting new scientific advancement. 
• Identify scientific gaps in current project and provide recommendations to the FTL for correction. 
• Work independently within project teams to design, develop and optimize analytical assays and provide assay support for clinical trial vaccine candidates. Write SOPs and publications if method is deemed innovative by FTL. 
• Reports to FTL weekly with progress and data packages. Bring assessment with suggestions, and target timelines. Thoroughly and accurately communicate scientific rational and findings to VPP leadership. 
• Design and execution of experiments for the development of analytical assays required for product development and clinical manufacturing.   
• Lead experimental design, carry out experiments, trouble shoot methods or help with trouble shooting material issues with solid methods. 
• Write and review technical protocols and reports documenting analytical development studies pertaining to his/her work and the work of the group.   

Specific Qualifications:

• PhD in biochemistry or an immunologist or related discipline with relevant years of experiences and capabilities. 
• 10 years in a related scientific discipline. 
• Have in-depth institutional knowledge on clinical development products including all VPP monoclonal antibodies, recombinant proteins for vaccine candidates, including virus-like particles (VLP) and nanoparticles.   
• Demonstrated analytical capabilities with techniques used in the analytical development in support of process and product development may include: Binding assays, Cell based assay, Residual immunoassays 
• A thorough understanding of protein analysis with experience in quantitative and qualitative protein analysis for assay development is required.  Knowledge of the requirements and experience developing, qualifying and/or validating assays for cGMP products and managing method transfers between laboratories is highly desirable.  The candidate will be involved in developing, characterizing, and transferring assays to the VRC pilot plant’s QC group for product release. 
• Demonstrate the ability to work well within a team, the candidate must be a team player who can effectively work with other research, development, and cGMP personnel. 

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com

Disclaimer:The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

Salary Range: $74,000 USD - $105,000 USD