Therapeutics Discovery Technician

Cape Fox subsidiary Eagle Health, LLC is accepting resumes for a Therapeutics Discovery Technician to support the members at Ft. Detrick, Maryland. This position is contingent upon contract award.

Incumbents are encouraged to apply!

The salary range (or hiring range) for this exempt position has been established at: $75,000-$84,000.

The above salary range represents the company’s good faith and reasonable estimate of the range of possible compensation at the time of posting. In addition, we offer a variety of benefits including company holidays, paid time off, health insurance, dental insurance, vision insurance, life and disability insurance, tuition reimbursement, as well as 401K with company match. This job will be posted until filled or withdrawn.

Responsibilities:

The employee shall provide laboratory support for research efforts of the MBD. Support shall be required in BSL-2 environment. employee shall provide support in the planning and conduct of basic and applied research on current and emerging threats in support of the BD and infectious disease program. The employee shall aid in the development and execution of scientific studies, basic cell culture, 3D bioprinting, stem cell maturation, spheroid/organoid development, PCR, high-throughput screening assays and/or high-throughput sequencing on infectious agents. Some other assays, such as animal procedures, collection/data analyzing, and maintaining laboratory and laboratory equipment may be required.

• Assist in the planning, development, execution and evaluation of high-throughput screening projects for the antibacterial, anti-viral, and anti-toxin therapeutic areas and assist in the development of novel assays/methods for various programs. This includes basic cell culture, stem cell maturation, 3D bioprinting, and spheroid/organoid development to support these efforts. Shall assist in screening of molecular compound libraries for therapeutic efficacy to support MCM development.
• Perform both in vitro and in vivo microbiological experiments designed to evaluate therapeutic compounds for antibacterial/antiviral/antitoxin activity. In vitro assays include enzymatic assays, cell-based phenotypic and reporter assays, Minimum Inhibitory Concentration (MIC) and plaque assays. Shall perform basic and advanced molecular biology techniques such as gene cloning, gel electrophoresis (such as DNA/RNA gels and Western blots) and transcriptomics (such as 10X genomic for bulk and spatial transcriptomics)
• Support BSL-2 mouse studies when required. Shall assist with inoculations of animals, collect specimens for processing, and analysis of those specimens. Analysis may include development and conduct of immunological procedures including Enzyme Linked immunoassay (ELISA), Western blot, and Mesoscale Discovery based assays.
• Assist in the preparation of technical reports, standard operating procedures, and manuscripts relating to their research efforts. The employee may be expected to present research findings at 1 scientific conference per year as needed and CONUS travel may be required. Employee shall present results in written and oral format publicly and internally as requested.
• Be responsible for assessing and maintaining laboratory supplies in BSL-2 laboratories. Shall assess supplies and ensure supply orders are coordinated with Division resources. Shall ensure that all assigned laboratory space is orderly and compliant with all regulatory guidance.
• Perform operations and training in animal manipulations. Employee shall support BSL-2 animal studies (mouse, hamsters, guinea pigs, etc.) for funded projects. Employee shall be experienced with handling both bacterial and viral pathogens for in vitro and in vivo studies.
• Provide the TPOC a Research Technical Report NLT the last day of each month.
• Communicate to the Lead/PI or assigned TPOC as applicable, unexpected experimental data/results and assist in the troubleshooting or root cause analysis. Employee shall communicate to the TPOC any laboratory or other task-related issues. Employee shall communicate with internal maintenance or external vendors for technical support and troubleshooting.
• Maintain an orderly laboratory environment in compliance with regulations. Employee shall coordinate ordering of supplies with division staff. Employee shall assist in training new personnel including students and other technicians as needed.
• Participate in regular laboratory decontamination and cleaning. Main laboratory areas, benches and hoods shall be decontaminated periodically to reduce possible sources of contamination. This task also includes proper disposal of waste and packaging material. Testing of emergency showers, eye washers and drainage systems shall be completed IAW applicable USAMRIID SOPs. Employee shall participate in regular instrumentation washes, cleaning, and maintenance.
• Maintain laboratory records documenting sample processing, protocol design and usage, and data management that meet current CGS and Institutional requirements and ensure continuity and collective sharing of resources. Employee shall assist in maintaining laboratory equipment, specimens, and reagents inventories, as well as keeping an organized, safe and professional work environment.
• May be required to cross-train and provide laboratory technical support to other areas within the MBD as needed.
• Present research findings/presentations at monthly lab meetings as required and attend scientific discussion weekly meetings.

Cape Fox Corporation, its subsidiaries, and affiliates provide equal employment opportunities to all persons and prohibit employment decisions on the basis of race, religion, color, creed, national origin, sex, age, disability, political affiliation, protected veteran status, or sexual orientation, or any other characteristic protected by federal, state, or local law. Cape Fox Corporation, its subsidiaries, and affiliates offer preference to Cape Fox Corporation Shareholders, descendants, and other Native Americans pursuant to Public Law 100-241.

• BSL-2, environment experience.
• Long hours and weekends may be required to meet deliverables.
• Strong written and oral communication skills, organizational skills, and attention to detail.
• Self-motivated with minimal oversight.
• Computer skills including Microsoft Word, Excel, PowerPoint, and Outlook.
• CONUS travel may be required.
• Must have authorization to work in the United States as defined by the Immigration Reform Act of 1986.
• Must be a US citizen with a valid U.S. passport, per contract requirements.