Director, Laboratory and Bioinformatics Research and Development, Oncology

Job Description

The Director, Laboratory and Bioinformatics Research and Development, Oncology role is to lead a group of cross-functional teams to support the development, validation and execution of clinical and research use products, develop high performing teams, and create new revenue streams by establishing and maintaining high quality and productive collaborative relationships with Company business and pharmaceutical partners, other commercial collaborators, CROs, KOLs, and academic groups.  The individual also provides strategic leadership in development and commercialization of transformative molecular diagnostic products and tools for clinical and research purposes. Additionally, the individual leads publication efforts across translation research, drug development and clinical utility space to support commercial success of these products.   

Primary duties and Responsibilities

Work with a cross functional group of teams to support the development of comprehensive molecular diagnostics tests. Lead the development of bioinformatics pipelines, data analysis, translational research, publication and data reporting efforts.

• Supervises, directs and coordinates day-to-day activities of workers engaged in Bioinformatics, laboratory research and development, data science and translational research activities.
• Lead the Research and Development (R&D) laboratory and test development activities, including LDTs and FDA approved/cleared assays, pharmaceutical services and operational laboratory enhancements
• Provides thought leadership and representation in interoperability work groups, as they relate to company’s framework.
• Provides strategic support to bridge laboratory, computational, commercial and clinical teams to advance company-wide initiatives.
• Lead translational and clinical utility publications for existing products to support sales and reimbursement efforts.
• Provides administrative/managerial oversight of the laboratory R&D, Bioinformatics, data science and translational research teams. 
• Directs technical and non-technical staff involved in developing, implementing and validating clinical and non-clinical processes to support NGS testing and biopharma services.
• Set clear expectations, give appropriate autonomy, guide team members; manage performance by providing feedback, guidance/teaching and development opportunities.
• Supervise and evaluate R&D team members across laboratory research and development, bioinformatics, data science and translational research team member performance, competency, proficiency and attendance.
• Coordinate work schedules for laboratory research and development, bioinformatics, data science and translational teams.
• Troubleshoot issues with staff through meetings, remote sessions with supporting departments, companies, literature, etc.
• Provides data for critical review of pipeline development and enhancements; monitors timelines to meet production goals and objectives.
• Lead technical evaluations and assay development activities as they pertain to new product development including, but not limited to, future iterations of OmniSeq INSIGHT, Whole Genome Sequencing, Whole Exome Sequencing, and Whole Transcriptome Sequencing.
• Lead applied research on novel computational / statistical methods, software tools and databases for analysis of genomes and transcriptomes, with a primary focus on gene expression profiling, predictive biomarkers, and disease-associated variant analysis.
• Develop, maintain, and analyze QC metrics to support internal R&D.
• Process, analyze and interpret high volumes of data.
• Prepare and deliver presentations to varied audiences.
• Work independently to prepare and meet timetables, deliverables, and project schedules.
• Publishes regularly in refereed journals and provides data, tables and figures as required.
• Represent Company at scientific conferences, presentations, and industry and investment groups.
• Ensures continuous delivery of bioinformatic services through oversight of service level agreements with end users and monitoring of systems, programs, and pipeline performance.
• Ensure standardization of key pharma product deliverables to promote high quality service.
• Lead key pharma and industry business development activities around research and development services.

Job Requirements

• PhD in Bioinformatics, Computational Biology, Genetics, Statistics, Biology, Biochemistry or similar field required.
• Prior experience in leading Bioinformatics, translational research, and/or laboratory-based research and development teams.
• Demonstrated experience in processing of high-volume genomic data generation and/or analysis including from technologies such as microarrays or NGS required. NGS data analysis highly preferred.
• Knowledge of human immune system and cancer biology required, direct experience in cancer research, including a working understanding of computational approaches for cancer genome and transcriptome analysis, highly preferred.
• Prior research experience and academic publications in data analysis for immune profiling and computational methods for immune response biomarker development in tissue and blood is a plus.
• Knowledge of commercial and open-source databases and proficiency in utilizing data from public resources such as TCGA, ICGC, COSMIC, HGMD, ClinVar etc. as part of data analysis or method development highly preferred.
• Experience in R, Python, Unix shell scripting or similar, with ability to understand and modify existing code as well as develop new scripts.
• Team oriented with excellent written and verbal communication skills.
• Ability to work in a fast-paced, dynamic, and results-oriented startup environment.

Machines, Tools and Equipment Used

• Personal computer
• NGS platforms
• TCGA, ICGC, COSMIC, HGMD, ClinVar databases

Relocation may be available.

Pay Range: $168,200 - $200,000 Annual Salary

All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. 

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan.  Casual, PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. For more detailed information, please click here. 

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. 

We encourage all to apply

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Salary : $168,200 - $200,000