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Scientific Director, Metabolite Profiling Core Facility

Massachusetts Institute of Technology- Koch Institute
Cambridge, MA Full Time
POSTED ON 4/2/2023 CLOSED ON 5/31/2023

What are the responsibilities and job description for the Scientific Director, Metabolite Profiling Core Facility position at Massachusetts Institute of Technology- Koch Institute?

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SCIENTIFIC DIRECTOR, METABOLITE PROFILING CORE FACILITY, Koch Institute (KI) for Integrative Cancer Research, to support metabolism-based research projects in a variety of experimental models through the use of high-resolution, accurate-mass, liquid chromatography mass spectrometry. Will oversee and further develop the operation of a state-of-the-art facility consisting of targeted and untargeted metabolomics and lipidomics platforms using high-resolution, accurate-mass, liquid chromatography mass spectrometry (LC/MS); collaborate with and advise scientists at KI, MIT, Whitehead Institute, and external institutions on developing and applying LC/MS-based metabolomic/lipidomic experiments to advance the research; participate in grant writing and manuscript preparation and on the acquisition of new equipment to expand and advance scientific applications; and supervise two research assistants who help with the day-to-day maintenance of the facility and participate in data analysis. In this highly collaborative position, responsibilities will include consulting on experimental design, analyzing and interpreting metabolomic/lipidomic data, and developing new LC/MS-based assays as projects dictate.

Job Requirements
REQUIRED: Ph.D. in biological/physical sciences or a related discipline; at least seven years' research experience, preferably in a biological/biomedical setting; comprehensive understanding of quantitative methods in mass spectrometry and metabolomics, including instrument operation, sample preparation, and data analysis; experience with lipidomics or willingness/ability to learn; strong communication, troubleshooting, and problem solving skills; ability to collaborate with scientists to consult on experimental design, data analysis, and interpretation; supervisory experience; and ability to work as part of a team. PREFERRED: working knowledge of Orbitrap systems and accompanying software, understanding of the use of stable isotopes in tracing experiments, and broad knowledge of high-resolution accurate-mass data analysis software. Job #22551



3/30/23

 

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