What are the responsibilities and job description for the Researcher 3 position at Ohio State University Wexner Medical Center?
The Pharmacoanalytical Shared Resource (PhASR) supports various clinical trials and drug development projects through the development and utilization of bioanalytical assays for ELISA and LC-MS/MS methodologies according to FDA guidance. The Researcher will be responsible for:
The application of in-depth knowledge of analytical chemistry and bioanalytical methodologies to drive efficient project design and implementation.
The development and validation of analytical assays using LC-MS/MS, ELISA, or other appropriate analytical platforms according to FDA guidelines.
Planning, development, and management of analytical methods to quantitatively characterize mechanisms of absorption, distribution, metabolism, and excretion of novel drugs or drug candidates.
Troubleshooting and maintenance of LC-MS/MS systems.
The preparation of biological specimens by protein precipitation, phospholipid removal, liquid-liquid and solid phase extraction for ELISA and LC-MS/MS analyses, and for analysis by other methods as appropriate.
Development and testing of experimental designs, sampling techniques and analytical methods to make recommendations for implementation.
Researching published studies and incorporating new knowledge and information into PhASR projects.
Maintaining accurate and detailed research records, including a laboratory notebook, method, and project related documentation.
Assisting with the preparation of method and project reports, research papers and manuscripts for publication and presentation at national conferences and workshops.
Assisting with day-to-day operations including receipt of samples and packages while completing appropriate documentation.
Performing FDA Bioanalytical method validation on newly developed and existing methods.
Following established laboratory safety procedures to ensure compliance with OSHA regulations and local, state, and federal regulations.
Serving as a resource for less experienced scientists.
Training others on developed protocols and laboratory procedures.
Performing additional duties as assigned.
Qualifications
Masters Degree, or equivalent experience in a bioanalytical laboratory is required, PhD preferred.
At least 5 years of experience with sample preparation and analysis using ELISA, LC-MS/MS, or flow cytometry. Hands-on experience with the development of LC-MS/MS or ELISA analytical methods.
Clinical sample analysis and/or FDA bioanalytical method validation would be preferred, but not required. 6 8 years of relevant experience preferred.
Function: Research and Scholarship
Sub Function: Research
Career Band: Individual Contributor - Specialized
Career Level: S3
The Ohio State University is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, or protected veteran status.
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nations largest and most comprehensive public universities and a top employer in Ohio.
As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies providing tomorrows standard of care today. A Cancer-Free World Begins Here.
The OSUCCC James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities. is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities.
Salary Range for this position: $64,300 - $84,550
Salary : $62,700 - $83,600
