What are the responsibilities and job description for the Research Scientist III position at Seattle Children's?
*Research Scientist – III*
Seattle, Washington I Research | Full time @ 40 Hours/Week | Regular & Day Shift | R242936
Summary Of Position
Create transformative genetic therapies for pediatric immune diseases in the beautiful Pacific Northwest. Dr. Mara Pavel-Dinu's laboratory seeks an experienced laboratory research scientist interested in hematopoietic cell therapies, gene editing, and translational immunology. The ideal candidate will help to lead a research team focused on studying, developing, and testing novel gene therapy approaches for treating blood and immune disorders (PMID: 38096800, PMID: 30967552, PMID: 39378586, PMID:33712802, PMID: 35773054). The research scientist will be part of a highly interactive, supportive, and inclusive research group, expanding upon our genome editing platform, murine models, and in vitro systems to maximize your potential to achieve high-impact publications and develop therapeutic products. The projects are collaborative and supported by institutional funding.
The newly established research group is part of the Center of Immunity and Immunotherapies (CIIT) of Seattle Children's Research Institute (SCRI), located in downtown Seattle, a city that is surrounded by lakes, the Puget Sound, and the Cascade and Olympic mountains- a great location for both urban and outdoor adventurers. Seattle Children's Research Institute and Pavel-Dinu Laboratory offer competitive salaries and a generous benefits package as a full-time employee.
Job Responsabilities
The ideal candidate will design, execute, and interpret experiments to generate and test pre-clinical models of hematopoietic stem cell-based and immune cell-based therapies in vitro and in vivo (mouse models). The candidate will meet regularly with the PI to discuss research progress and next steps. The candidate will present data at internal and external meetings and contribute to manuscripts, grants, and patents. Under PI supervision, the candidate will also manage and mentor junior scientists, undergraduates, and graduate students.
Knowledge, Skills And Abilities
*Required Education and Experience*
PhD Degree level in applicable science field/related field OR.
Master's Degree in applicable science field/ related field plus minimum three (3) years of related experience OR.
Bachelor's Degree or higher in applicable science field / related field plus minimum five (5) years of related experience with a robust publication record.
Related work experience varies by lab / position, as it relates to the research projects and research field assigned to this position.
*Required Credentials*
N/A.
*Preferred*
PhD in relevant specialty area or closely related field.
Substantial prior experience in relevant area of research.*Compensation Range*
$78,735.00 - $118,103.00 per year*Salary Information*
This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.
*Disclaimer for Out of State Applicants*
This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors*.*
*Benefits Information*
Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website [www.seattlechildrens.org/careers/benefits](https://www.seattlechildrens.org/careers/benefits).
*About Us*
*Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE*
Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.
In 2022, U.S. News & World Report once again ranked Seattle Children’s among the nation’s best children’s hospitals – for the 30th year in a row. For more than a decade, Seattle Children’s has been nationally ranked in all 10 specialty areas evaluated by U.S. News & World Report. We are honored to be the top-ranked pediatric hospital in Washington and the Pacific Northwest.
As a Magnet designated institution, and classified among America’s best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.
*Our Commitment to Diversity*
Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.
Seattle, Washington I Research | Full time @ 40 Hours/Week | Regular & Day Shift | R242936
Summary Of Position
Create transformative genetic therapies for pediatric immune diseases in the beautiful Pacific Northwest. Dr. Mara Pavel-Dinu's laboratory seeks an experienced laboratory research scientist interested in hematopoietic cell therapies, gene editing, and translational immunology. The ideal candidate will help to lead a research team focused on studying, developing, and testing novel gene therapy approaches for treating blood and immune disorders (PMID: 38096800, PMID: 30967552, PMID: 39378586, PMID:33712802, PMID: 35773054). The research scientist will be part of a highly interactive, supportive, and inclusive research group, expanding upon our genome editing platform, murine models, and in vitro systems to maximize your potential to achieve high-impact publications and develop therapeutic products. The projects are collaborative and supported by institutional funding.
The newly established research group is part of the Center of Immunity and Immunotherapies (CIIT) of Seattle Children's Research Institute (SCRI), located in downtown Seattle, a city that is surrounded by lakes, the Puget Sound, and the Cascade and Olympic mountains- a great location for both urban and outdoor adventurers. Seattle Children's Research Institute and Pavel-Dinu Laboratory offer competitive salaries and a generous benefits package as a full-time employee.
Job Responsabilities
The ideal candidate will design, execute, and interpret experiments to generate and test pre-clinical models of hematopoietic stem cell-based and immune cell-based therapies in vitro and in vivo (mouse models). The candidate will meet regularly with the PI to discuss research progress and next steps. The candidate will present data at internal and external meetings and contribute to manuscripts, grants, and patents. Under PI supervision, the candidate will also manage and mentor junior scientists, undergraduates, and graduate students.
Knowledge, Skills And Abilities
- Hands-on experience in molecular biology, cell culture, assay development, and flow cytometry analysis.
- Expertise in stem cell biology and immunology is highly desirable
- Expertise in mouse model-based studies: surgical procedures, anesthesia, injection techniques (IP, IV, SC, IM, and RO), blood collection techniques (tail vein, retro-orbital sinus, saphenous vein, cardio puncture), physiological assessments, behavioral testing, drug administration, transplantation techniques (IF, IH, RO), and end-point FACS-based analyses is highly desirable
- Immunological techniques (not limited to): immunohistochemistry, cytokine profiling, enzyme-linked immunospot assays
- Cellular and molecular assays (not limited to): DNA/RNA extraction, purification, cell culture, cytotoxicity assays, cell proliferation, PCR, qPCR, RT-PCR, and ddPCR are highly desirable
- Biochemical assays (not limited to): reporter gene assays, enzyme activity assays
- Comfortable in a fast-paced environment and able to work collaboratively.
- Have excellent interpersonal, verbal, and written communication skills
- Effective analytical and problem-solving skills
*Required Education and Experience*
PhD Degree level in applicable science field/related field OR.
Master's Degree in applicable science field/ related field plus minimum three (3) years of related experience OR.
Bachelor's Degree or higher in applicable science field / related field plus minimum five (5) years of related experience with a robust publication record.
Related work experience varies by lab / position, as it relates to the research projects and research field assigned to this position.
*Required Credentials*
N/A.
*Preferred*
PhD in relevant specialty area or closely related field.
Substantial prior experience in relevant area of research.*Compensation Range*
$78,735.00 - $118,103.00 per year*Salary Information*
This compensation range was calculated based on full-time employment (2080 hours worked per calendar year). Offers are determined by multiple factors including equity, skills, experience, and expertise, and may vary within the range provided.
*Disclaimer for Out of State Applicants*
This compensation range is specific to Seattle, positions located outside of Seattle may be compensated differently depending on various factors*.*
*Benefits Information*
Seattle Children’s offers a generous benefit package, including medical, dental, and vision plans, 403(b), life insurance, paid time off, tuition reimbursement, and more. Additional details on our benefits can be found on our website [www.seattlechildrens.org/careers/benefits](https://www.seattlechildrens.org/careers/benefits).
*About Us*
*Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE*
Our founding promise to the community is as valid today as it was over a century ago: we will care for all children in our region, regardless of the families’ ability to pay. Together, we deliver superior patient care, advance new discoveries and treatments through pediatric research, and serve as the pediatric and adolescent, academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country.
In 2022, U.S. News & World Report once again ranked Seattle Children’s among the nation’s best children’s hospitals – for the 30th year in a row. For more than a decade, Seattle Children’s has been nationally ranked in all 10 specialty areas evaluated by U.S. News & World Report. We are honored to be the top-ranked pediatric hospital in Washington and the Pacific Northwest.
As a Magnet designated institution, and classified among America’s best large employers by Forbes, we recognize the importance of hiring and developing great talent to provide best-in-class care to the patients and families we serve. Our organizational DNA takes form in our core values: Compassion, Excellence, Integrity, Collaboration, Equity and Innovation. Whether it’s delivering frontline care to our patients in a kind and caring manner, practicing the highest standards of quality and safety, or being relentlessly curious as we work towards eradicating childhood diseases, these values are the fabric of our culture and community. The future starts here.
*Our Commitment to Diversity*
Our community welcomes diverse experiences, backgrounds, and thoughts as this is what drives our spirit of inquiry and allows us to better connect with our increasingly diverse patients and families. Our organization recruits, employs, trains, compensates, and promotes without regard to race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.
The people who work at Seattle Children’s are members of a community that seeks to respect and celebrate all the qualities that make each of us unique. Each of us is empowered to be ourselves within this community, which cultivates and promotes equity, diversity, and inclusion at all levels.
Seattle Children’s is proud to be an Equal Opportunity Workplace and Affirmative Action Employer.
Salary : $78,735 - $118,103
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