Assistant Scientist

Job Title: Assistant Scientist

Duration: 12 months on W2 Contract (Possible Extension)

Location: Seattle, WA (Onsite)

Job Description:

Top Skills:

• Hands-on experience in upstream (cell culture, bioreactor operation, and transfection conditions) and downstream (depth filtration, normal flow filtration, tangential flow filtration, chromatography) unit operations for viral vector production.
• Prepare buffers and process solutions for pilot scale productions B.S in life sciences or engineering. 0-2 experience in biotech or engineering field. preferred skills upstream cell culture and/or downstream purification techniques of bi-molecules (chromatrography, filtration)

We are seeking an enthusiastic, self-driven individual to join the Gene Delivery & Editing Process Development team. Our team develops process and technology underpinning critical raw materials used in the manufacturing of engineered T cells, including viral vector.

The primary focus of this Assistant Scientist position will be to support upstream and downstream operations in our 250 L pilot lab for production of AAV and Lentiviral vectors used for gene delivery and gene editing of our cell therapy products. This team member will support current programs, advance process development of scalable, manufacturing-friendly viral vector processes, and provide non GMP grade viral vector for pipeline supporting studies. Join us and be part of a team that values collaboration, personal development, and diversity in pursuit of an inclusive and motivating work environment.

Responsibilities:

• Hands-on experience in upstream (cell culture, bioreactor operation, and transfection conditions) and downstream (depth filtration, normal flow filtration, tangential flow filtration, chromatography) unit operations for viral vector production

• Prepare buffers and process solutions for pilot scale productions

• Contribute to planning and design of experiments, execution and independent analysis of data.

• Maintain proper documentation of process data.

Basic Qualifications:

• M.S. or B.S. in Chemical Engineering, Bioengineering, Biochemistry, Molecular Biology, Virology, or related disciplines

• 0-2 years of industry experience in process development or related work

• Independently motivated with the ability to multitask and work in teams

• Ability to communicate clearly and concisely through oral presentation and technical writing

Preferred Qualifications:

• Demonstrated ability to read and understand scientific literature

• Experience in mammalian cell culture and aseptic techniques

• Experience with downstream equipment and techniques (Chromatography/AKTA, UF/DF, Sterile Filtration)

• Familiar with statistical analysis and experimental design

• Familiar with general analytical assays, such as HPLC and ELISA.

Additional Job Requirements:

Position Handles Hazardous Materials