What are the responsibilities and job description for the Scientist I, Proteomics position at Vividion Therapeutics, Inc?
Description
Company Overview:
Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.
We are uniquely structured with opportunities for all scientists to contribute to both established programs as well as ongoing early target selection, screens and validation. We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.
Vividion was ranked #2 mid-size company on The San Diego Union-Tribune's 2022 and 2023 Top Workplaces list.
Job Summary:
The successful candidate will have hands-on experience with different proteomics sample preparation techniques (i.e. chemical biology, AP-MS, PTM enrichment) and liquid chromatography-mass spectrometry, including method development and instrument maintenance. This position will help discover novel small-molecule ligands of protein targets through the execution of screens using our novel mass spectrometry-based proteomics platforms. This position will also support programs as the proteomics point-person as they progress from enablement to clinical implementation and work on new development projects to increase the platform group capabilities and throughput.
Requirements
Education and Experience requirements:
- Ph.D. (or equivalent experience) in mass-spectrometry based proteomics, analytical chemistry, chemical biology, or related discipline
- Extensive hands-on experience with LC-MS maintenance and operation of Thermo Orbitrap mass spectrometers. Experience with Thermo Tribrid instruments is highly desired
- Demonstrated ability to apply and troubleshoot complex proteomics techniques in a biological context (isobaric labeling techniques, phosphoproteomics and/or other PTM enrichments, IP-MS)
- Experience with global proteomics (TMT and/or DIA) data analysis. Experience analyzing data in Skyline is a plus
Required Key Attributes:
- Candidates must have strong communication skills and an ability to present results to large teams
- Candidates must have effective troubleshooting and problem-solving skills.
- Candidates must be an effective team player, strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines.
Pay & Benefits:
The annual base salary for this position ranges from $110,000 to $120,000 depending on relevant skills, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance.
EEO & Employment Eligibility:
Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Privacy Policy:
The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https://vividion.com/publication/privacy-noticeforcalifornia-candidates/.
Salary : $110,000 - $120,000