SVP, Primary Focus Lead, Targeted Protein Degradation

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .

This position is based in Northbrook, Illinois. Remote work from certain states may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

Purpose and Scope:

The Primary Focus Lead (PFL) provides leadership and strategic direction for research, development, manufacturing, and commercialization of the Primary Focus pipeline globally. PFL manages complex portfolio of including 20 research and development stage projects and 4 modality platforms. PFL determines extension of PF, resource allocation and pipeline priorities, leads execution and accountable for related budget. PFL chairs PF TPD LT and collaborates with the relevant Divisions to achieve PF goals.

Essential Job Responsibilities:

Create and revise PF Strategy to define the direction, capability and resource need of the diverse PF modalities and pipeline (EC)

Create the PF Roadmap to define execution plan and consolidated PF budget

Update strategy and roadmap driven by the rapidly changing scientific and competitive environment

Chairs PF TPD LT, lead representatives of relevant functions to develop PF Strategy and implement the Roadmap, and guide Asset Teams and Research functions

Motivates and creates unique culture to drive high performance

Drives continuous investment into the PF, on order to evolve it and maximize its value

Monitors and reports progress of projects in each PF per Roadmap

Define the PF Business Development strategy to evolve Primary Focus. Collaborates with BD and CS to evaluate external assets and drives decision in Corporate Governance

Endorse project team’s proposal at KC

Creates PF budget and accountable for budget spending through Functional Units

Represents Astellas in committees and external scientific/ industry forums

Estimated Operating Budget: 222.0 oku yen R&D budget, PFL is accountable for planning and execution

Future revenue impact is significant

Global scope, impacts several divisions and /broad pipeline in multiple research and development stages

Other: strategy and milestone decisions impact overall value of Astellas pipeline and valuation

Core member of KC (portfolio governance). Chair of the PF TPD LT. Chair of Joint Steering Committees of external research collaborations

Reports to CRDO

Executive Committee and other Governance Committee members

Head of Oncology Research, Head of Oncology Development, Head of Early Dev, Head of Regulatory/PV, BD, CS, Finance, Commercial, Market Access

CEO/CBO/CSO of partner biotech (Cytomx, Kalivir, Kelonia, etc.), other PFLs

Leaders of external companies related to BD and research activities

Key External Experts, Scientific Advisory Board Members

Represents Astellas TPD in investor, business, scientific community

Qualifications:

Required

Master Degree. MD, PhD, or PharmD preferred.

15-20 year experience in cancer drug development in pharma industry

Capability to develop strategy and solutions for unprecedented, novel business areas

Capable of setting direction of complex matrix organization

Inspirational, collaborator both externally and internally

Salary Range

$400k-$470K (NOTE: Final salary could be more or less, based on experience)

Benefits:

Medical, Dental and Vision Insurance

Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks

401(k) match and annual company contribution

Company paid life insurance

Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions

Long Term Incentive Plan for eligible positions

Referral bonus program

Category PFL-Oncology

Astellas is committed to equality of opportunity in all aspects of employment.

EOE including Disability/Protected Veterans