Research Technician II

Position Overview

A leading biotechnology research organization is seeking a highly talented and passionate Research Technician II to join a specialized team focused on cutting-edge functional genomics research. This role will support the implementation and development of large-scale, high-throughput DNA cis-regulatory element screening technologies.

Position Details

Location: South San Francisco, CA (On-site)

Start Date: As soon as possible

Duration: 6 months with possibility for extension

Compensation: $31-$41/hour

Key Responsibilities

• Design, execute, and optimize complex genomics protocols including custom DNA/RNA amplicon preparation and sequencing.
• Perform massively parallel reporter assay (MPRA) screens in diverse cell systems.
• Conduct primary cell culture work, including specialized cell types as needed.
• Execute molecular biology techniques including molecular cloning, flow cytometry, and quantitative PCR.
• Work with viral vector technologies and next-generation sequencing library design/generation.
• Analyze and interpret experimental data, communicating results effectively to the team.
• Contribute to team-based science and technology development initiatives.
• Maintain detailed experimental records and documentation.
  
  

Required Qualifications

• Bachelor's, Master's, or Ph.D. degree in Biology, Genetics, Biomedical Engineering, or related field.
• 2-5 years of relevant laboratory research experience.
• Demonstrated expertise in designing and executing cell and molecular biology experiments.
• Experience with primary cell culture (required).
• Proficiency in standard molecular biology techniques.
• Passion for scientific discovery and commitment to continuous learning.
  
  

Preferred Qualifications

• Experience with massively parallel reporter assays (MPRA).
• iPSC and/or T cell culture experience.
• Expertise in viral vector technology (lentivirus).
• Background in NGS library design and generation.
• Experience with scRNA-seq and/or scMPRA technologies.
  
  

This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!

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