What are the responsibilities and job description for the LAB RESEARCH ANALYST I position at Duke University?
School of Medicine
Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.
The Global Health Discovery Collaboratory (GHDC) Antibody Dynamics team at the Duke University Center for Human Systems Immunology (https://chsi.duke.edu/divisions/antibody-dynamics-and-immune-function) is seeking a detail-oriented scientist to fulfill a key role as Research Analyst 1. The incumbent of this position in the Biophysical Immunology team will perform assays to assess the kinetics of antibody-antigen interactions in therapeutic antibody development and in responses to vaccination against global health pathogens including those that cause malaria and tuberculosis. The study results generated by the person in this role will inform human clinical and pre-clinical trials for vaccines, accelerate antibodies and other biologics candidates to clinic. The person in this role will also play a key role in assay development and standardization and in testing feasibility of novel methods. This person must be very organized, possess excellent communication skills, have a high level of technical precision, be interested in assay development and optimization, enjoy working in a fast-paced lab environment with multiple priorities, and be able to work well as part of a team. Job functions include:
Education
Work requires a bachelor's degree in botany, biology, zoology,psychology or other directly related scientific field.
Experience
Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.
Minimum Qualifications
Education
Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly relatedscientific field.
Experience
Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.
Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.
The Global Health Discovery Collaboratory (GHDC) Antibody Dynamics team at the Duke University Center for Human Systems Immunology (https://chsi.duke.edu/divisions/antibody-dynamics-and-immune-function) is seeking a detail-oriented scientist to fulfill a key role as Research Analyst 1. The incumbent of this position in the Biophysical Immunology team will perform assays to assess the kinetics of antibody-antigen interactions in therapeutic antibody development and in responses to vaccination against global health pathogens including those that cause malaria and tuberculosis. The study results generated by the person in this role will inform human clinical and pre-clinical trials for vaccines, accelerate antibodies and other biologics candidates to clinic. The person in this role will also play a key role in assay development and standardization and in testing feasibility of novel methods. This person must be very organized, possess excellent communication skills, have a high level of technical precision, be interested in assay development and optimization, enjoy working in a fast-paced lab environment with multiple priorities, and be able to work well as part of a team. Job functions include:
- Design and perform high throughput surface plasmon resonance (SPR) and bio-layer interferometry (BLI) assays to identify lead monoclonal antibody and other biologics candidates for therapeutics development.
- Perform complex and highly technical BLI and SPR assays in the laboratory to evaluate antibody dynamics in samples from clinical and preclinical vaccine trials. Carefully and accurately document assay conditions, results, and quality control findings and report them promptly to meet deadlines.
- Play a key role in the development and standardization of new assays, participating in discussions of next steps for follow up assays and in assay design.
- Perform bio-layer interferometry (BLI), surface plasmon resonance (SPR), and other assays in the lab to develop new methods and protocols, optimize reagents, test various conditions, and determine feasibility of assays using novel antigens.
- Assist with data analysis, data presentation and writing of summary, qualification and validation documents.
- Assist the laboratory and project managers by contributing to the overall effort to streamline the
- Maintain laboratory and associated equipment in a clean, well-ordered, and functional manner. Keep supplies on hand with a well-planned inventory and ordering system.
- Maintain laboratory notebook in an orderly fashion for tracking experiments and results. Provide written updates of work each week.
- Bachelor’s degree in Chemistry, Biochemistry, Biophysics, Bioengineering, Biotechnology, biological science or related field,
- Strong background in laboratory techniques with technical precision
- Two years of research experience performing SPR/BLI assays or equivalent combination of relevant education and research experience
- Must be able to manage multiple and rapidly changing priorities and have the ability to quickly learn new skills
- Must be detail-oriented and well organized with strong communication skills and the ability to work in a fast-paced interactive team environment.
- Experience in using Mathematica and R-studio packages and working in GMP/GCLP compliant laboratories will be a plus.
Education
Work requires a bachelor's degree in botany, biology, zoology,psychology or other directly related scientific field.
Experience
Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.
Minimum Qualifications
Education
Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly relatedscientific field.
Experience
Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.
Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
