Analytical Scientist

Essential Functions:

• Develop advanced and robust LC-MS analytical methods for the bioanalysis of different molecular formats such as small molecules, oligonucleotides, peptides, and/or proteins.
• Develop and implement innovative high-resolution mass spectrometry-based metabolite profiling and identification platforms
• Perform LC-MS-based small molecule biomarker analysis occasionally
• Review and translate complex LC-MS-based data sets and articulate findings to project teams
• Maintain/document records of all experiments, including QC review data, experimental results, and reports as appropriate into electronic laboratory notebooks
• Contribute to the team’s knowledge through updating scientific literature and discussions
• Maintain and troubleshoot lab instruments such as biological sample extraction systems, HPLC, and LC-MS

Qualifications:

Required:

• PhD or Master’s degree in pharmaceutical sciences, analytical chemistry, chemistry, biochemistry or related disciplines with relevant experience from industry or academia required. (Fellowship work can be counted as relevant experience, but preference will be given to a scientist with CRO bioanalysis experience)
• See top of JD for required years of experience by level
• Demonstrable superior laboratory skills in biological sample extraction, chromatography, and/or quantitative/qualitative Mass Spectrometry.
• Experience with bioanalysis of different molecular formats such as small molecules, peptides, oligonucleotides and/or proteins.
• Self-motivated with a proactive mindset
• Ability to thrive in a multi-disciplinary and fast-paced research environment with tight deadlines

Preferred:

• Experience with LC-MS-based ADME and/or bioanalytical assays
• Experience with Sciex Analyst™, OS, Xcalibur™ and/or other Mass Spectrometry data-acquisition software packages
• Knowledge of guidance for industry bioanalytical method validation