Scientist

A global Pharmaceutical company that harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Our investment in research and development has yielded a robust pipeline that builds on our existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases.

Making a positive difference in the world is at the heart of what we do. Join us to make a difference!!

Skill Sets:

• Strong scientific foundation in the understanding and implementation of a wide range of cell-based assays (e.g., TR-FRET, BRET, AlphaLISA, HCS, luminescence and fluorescence-based reporter and/or label-free assays)
• Track record of developing, implementing, and performing novel cell-based screening assays in microtiter plates to support early drug discovery research
• Ability to design and implement gene editing (CRISPR knock out/in) workflows enabling the development of targets specific and disease-relevant cell-based assays

Project Scope:

• The development and optimization of novel cell-based assays ensure successful implementation and routine execution of these assays to support HTS, lead optimization, and mechanism-of-action studies for promising therapeutic targets.
• Design, implement, and optimize gene-editing workflows in a manner that enables development and evaluation of cell-based functional assays supporting therapeutic target screening or lead optimization studies.
• Investigate, identify, develop, and optimize new methods/techniques to generate reliable and reproducible data promptly.
• Semi-independently plan and implement experiments, adapt readily to changing project needs and develop sophisticated problem-identification and problem resolution skills.
• Maintain proficiency with the latest scientific literature and rationale surrounding drug targets and be an active contributor to the interpretation of results in group discussions.
• Adherence to good laboratory conduct, documentation practices, and safety guideline

Basic Qualifications:0 Years w/ Relevant PhD OR equivalent (where applicable) 2 Years w/ Relevant MS OR equivalent 4 Years w/ Relevant BS